Current Funding Opportunities
HHS OMH is pleased to announce the anticipated availability of funds for Fiscal Year (FY) 2026 under the authority of 42 U.S.C. § 300u-6 (Section 1707 of the Public Health Service Act):
National Lupus Outreach and Clinical Trial Education Program
Announcement Number: MP-CPI-26-001
Estimated Number of Awards: 6
Estimated Total Program Funding: $3,000,000
Anticipated Award Amount: Up to $500,000
Application Due Date: July 10, 2026, 6 p.m. ET
HHS OMH is accepting applications for projects to implement integrated, community-based models that increase participation of underrepresented populations in lupus clinical trials across the full participation pathway, including awareness, referral, screening, enrollment and retention.
Systemic lupus erythematosus (lupus) is a chronic autoimmune disease that causes inflammation across multiple organ systems, resulting in a wide range of clinical complications and ongoing challenges in disease management. Groups disproportionately affected by lupus are more likely to experience earlier disease onset, higher disease activity, and increased risk of complications.
Projects funded under the initiative will reduce lupus-related adverse health outcomes and support outreach, education, and partnerships that move beyond awareness building to measurable participation outcomes, including screening, enrollment, and retention in lupus clinical trials.
Visit Grants.gov for the full announcement on this opportunity.
| Grant program | National Lupus Outreach and Clinical Trial Education Program |
|---|---|
| Opportunity number | MP-CPI-26-001 |
| Grant listing | https://www.grants.gov/search-results-detail/362747 |
| Contact mailbox | MinorityHealth@hhs.gov |
Funding and budget
FAQ 1. Is the $500,000 anticipated award amount per year or the total ceiling for the full 36-month period of performance?
The funding amount is up to $500,000 for each 12-month budget period, not $500,000 total for the full 36-month period. Applicants may request up to $500,000 in direct costs per year for a project period of up to three years and should include budget information for each subsequent budget year as instructed in the NOFO. Continuation funding for years 2 and 3 is contingent upon the availability of funds, satisfactory progress, appropriate stewardship of federal funds, and the best interests of the government.
FAQ 2. Should applicants budget to the full $500,000 ceiling?
Applicants should request only the amount needed to carry out the proposed scope of work, up to the $500,000 per 12-month budget period ceiling and should fully justify requested costs in the budget narrative.
FAQ 3. Are indirect costs capped at 8 percent per year?
Yes. The indirect costs may not exceed 8 percent of allowable direct costs, in accordance with the funding announcement.
FAQ 4. Are subcontracts or partner subawards capped at $10,000?
No. Subcontracts are not capped at $10,000. Subcontract costs should be proposed as necessary to support the project and should be adequately justified in the budget narrative.
Partnerships and documentation
FAQ 5. If Letters of Commitment from clinical trial site partners are not finalized at submission, may applicants submit a written plan to establish the partnerships after award?
If Letters of Commitment (LOCs) are not ready, describe the partnership in detail - identify the partner, explain their role, and provide a timeline. Include supporting documents if possible. Do not submit general letters of support; only Memorandums of Agreement (MOAs) and LOCs are considered. Fully executed MOAs may be required within 30 days of project start.
Application forms, attachments, and personnel documentation
FAQ 6. Are two-page TransCelerate Abbreviated CVs acceptable for clinical trial site staff?
Yes. The logged OMH response states that abbreviated CVs for clinical trial site staff are acceptable. OMH prefers NIH-style biosketches for the PI/PD and other core project personnel, such as a project coordinator or manager, biostatistician, or evaluator.
FAQ 7. How should applicants handle the mandatory SF-LLL Lobbying Activities form if they have no lobbying activities or the form status shows as in progress?
For Grants.gov system navigation and troubleshooting, applicants should contact the Grants.gov Support Center at support@grants.gov. Applicants should provide supporting details such as the Funding Opportunity Number or Package ID, form name and version number, a detailed description of the issue, Grants.gov username, and UEI (SAM), as applicable.
Compliance requirements
FAQ 8. Do Intergovernmental Review requirements under Executive Order 12372 apply to this program?
Yes. The logged OMH response confirms that Intergovernmental Review requirements under Executive Order 12372 apply to this program. Applicants should follow the applicable Intergovernmental Review requirements when preparing their applications.
Technical Assistance webinar
FAQ 9. Where can applicants find the Lupus Clinical Trial Technical Assistance webinar link or recording?
The logged response directs applicants to the Lupus Program section of the HHS Office of Minority Health Funding Opportunities webpage for the Technical Assistance webinar link or related webinar information.
OMH Funding Opportunities page: https://minorityhealth.hhs.gov/hhs-omh-funding-opportunities
Center for Indigenous Innovation and Health
Announcement Number: MP-CPI-26-002
Expected Number of Awards: 2 - 4
Estimated Total Program Funding: $2,000,000
Award Ceiling: $1,000,000
Award Floor: $500,000
Application Due Date: July 15, 2026, 6 p.m. ET
HHS OMH is accepting applications for projects under the Center for Indigenous Innovation and Health (CIIH) initiative. The CIIH will support efforts, including research, education, service, partnership development, and technical assistance, to address the documented chronic disease burden and health care access gaps experienced by American Indian and Alaska Native (AI/AN) and Native Hawaiian and Pacific Islander (NHPI) populations.
National data continue to show that AI/AN and NHPI populations experience elevated rates of certain chronic and preventable health conditions compared to the national benchmarks, and these health outcomes are associated with community conditions such as food access, health literacy, education, health care availability, environmental exposure, language access, and access to health-promoting resources and services.
Projects funded under the initiative should implement evidence-based frameworks and community-based strategies to prevent and improve chronic disease outcomes, including obesity, hypertension, diabetes, and related conditions, within one Indigenous population of focus and a defined geographic area.
Visit Grants.gov for the full announcement on this opportunity.
| Grant program | National Lupus Outreach and Clinical Trial Education Program |
|---|---|
| Opportunity number | MP-CPI-26-002 |
| Grant listing | https://www.grants.gov/search-results-detail/362800 |
| Contact mailbox | MinorityHealth@hhs.gov |
Eligibility
FAQ 1. Are federal agencies, such as the Indian Health Service, eligible to apply?
No. The federal agencies such as the Indian Health Service are not eligible to apply for this type of funding. Applicants should refer to Section A: Eligibility Information of the NOFO for the eligible entity types and requirements.
Funding and budget
FAQ 2. Is the CIIH budget maximum $1,000,000 per year or $1,000,000 for the full two-year project period?
The funding ceiling for CIIH is between $500,000 and $1,000,000 per year. Applications should not exceed $1,000,000 for any single one-year period.
FAQ 3. If an applicant proposes a 24-month project, should the application include a second-year budget?
The program is offering a 24-month project period, not a 24-month budget period. Applicants should request the funding needed for the first 12 months only, with the option for second-year funding later; Year 1 and Year 2 funding should not be requested together in the initial application.
- The SF-424 and SF-424A should reflect only the first 12-month budget period.
- A one-year budget is acceptable and is the standard approach.
- Do not include Year 1 and Year 2 funding together in the initial SF-424 or SF-424A totals.
- Each Non-Competing Continuation (NCC) application serves as the funding request for the next year; Year 2 funding would be requested through the NCC process, subject to applicable continuation funding requirements.
Indirect costs and training-related activities
FAQ 4. Is CIIH a training grant, and how does the 8 percent indirect cost cap apply?
CIIH is not a training grant and the language referenced in the NOFO is standard language used across funding platforms. However, if an organization charges training-related activities to the grant, those training-related activities are subject to the 8 percent indirect cost cap. Even if an organization has a negotiated indirect cost rate above 8 percent, indirect costs associated with training activities may not be charged above 8 percent.
Project design, equipment, and technology
FAQ 5. Can a proposed project focus on deploying portable x-ray equipment, robotic ultrasound, or similar technology?
Projects should not be centered solely on deploying equipment or purchasing technology. A competitive application should demonstrate how the proposed activities support the overall purpose of CIIH. If portable x-ray equipment, robotic ultrasound, or other technology is included, the application should explain how the tools fit within a broader project model, address documented chronic disease burdens or access gaps, involve appropriate partners, justify costs, and support outcome measurement during the period of performance.
- Use an evidence-based framework.
- Engage community partners.
- Incorporate data collection and evaluation.
- Show measurable outcomes related to chronic disease prevention or improvement for the selected Indigenous population.
FAQ 6. Can OMH confirm whether a preliminary project idea will be responsive or funded?
Information shared during the pre-application period is general technical assistance and does not guarantee that a proposed project will be deemed responsive, allowable, or funded. Applicants should rely on the posted NOFO and Grants.gov listing as the authoritative sources and should ensure the application clearly aligns with the program purpose, eligibility and responsiveness requirements, budget expectations, and merit review criteria.
Technical Assistance webinar
FAQ 7. Where can applicants find webinar registration or access information for CIIH?
The logged OMH response states that webinar information, including the access link, will be available on the HHS Office of Minority Health Funding Opportunities webpage. Applicants should visit that page for webinar details and updates.
OMH Funding Opportunities page: https://minorityhealth.hhs.gov/hhs-omh-funding-opportunities
Application materials and Objective Work Plan
FAQ 8. The NOFO states that an Objective Work Plan template is provided in the application materials on Grants.gov, but I cannot locate it. Will the template be made available?
OMH recommends using the suggested optional workplan template to respond to the Objective Work Plan requirement. Applicants should review the application materials on Grants.gov and use the suggested optional workplan template, as applicable, when preparing the Objective Work Plan for submission.
Optional Work Plan Template
| GOAL #1: (State the Overall Project Goals in the Application) | ||||
|---|---|---|---|---|
| Objectives | Activities/Tasks | Responsible Persons | Timeframe | Expected Outcomes |
| Objective 1 Sub-objective 1.1 Sub-objective 1.2 | First activity/task Second activity/task | Responsible person for first activity/task Responsible person for second activity/task | Timeframe for first activity Timeframe for second activity | By X time, Y number or % of the target population will be Z result. By X time, Y number or % of the target population will be Z result. |
Date Last Reviewed: July 2026