HIV/AIDS and American Indians/Alaska Natives

American Indian/Alaska Native males had an HIV infection rate that was 29% lower than the total male population in 2023.1
In 2023, American Indian/Alaska natives 13 and older were diagnosed with HIV at a rate that was 39% lower than the total population.1
In 2023, American Indian/Alaska Natives with HIV died at a rate that was 46% lower than the total population.2 The rate for AIDS deaths was 49% lower than the total population.3
- In 2023, American Indian/Alaska Native males with HIV infection died at a rate that was 53% lower than the rate of total male population.
- In 2023, American Indian/Alaska Native females with HIV died at a rate that was 24% lower than the total population of females.

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Occurrence

Human Immunodeficiency Virus (HIV)

All Ages

Diagnoses of HIV infection, rate per 100,000 population, 2023
AI/AN	Total Population	Ratio (AI/AN / Total)
8.3	11.6	0.72

Source: U.S. Centers for Disease Control and Prevention. (2024). HIV surveillance report: Diagnoses, deaths, and prevalence of HIV in the United States and 6 territories and freely associated states, 2023 (Vol. 35, Table 1a). U.S. Department of Health and Human Services.

Adults and Adolescents

Diagnoses of HIV Infection among persons ages 13 and older, rate per 100,000 population, 2023
	AI/AN	Total Population	Ratio (AI/AN / Total)
Male	15.9	22.5	0.71
Female	4.0	5.1	0.78
Total	8.3*	13.7	0.61
*Total rate may include children <13

Source: U.S. Centers for Disease Control and Prevention. (2024). HIV surveillance report: Diagnoses, deaths, and prevalence of HIV in the United States and 6 territories and freely associated states, 2023 (Vol. 35, Tables 3a and 1a). U.S. Department of Health and Human Services.

Persons 13-24 years old living with diagnosed HIV infection, rate per 100,000 population, 2023
AI/AN	Total Population	Ratio (AI/AN / Total)
23.2	53.3	0.44

Children

Diagnoses of HIV infection among children ages 12 and under, rate per 100,000 population, 2023
AI/AN	Total Population	Ratio (AI/AN / Total)
0.3	0.1	3.00

Acquired Immune Deficiency Syndrome (AIDS)

Prevalence of AIDS among persons age 13 and older, rate per 100,000 population, 2023
	AI/AN	Total Population	Ratio (AI/AN / Total)
Male	104.5	292.5	0.36
Female	33.0	87.4	0.38
Both Sexes	68.0	188.3	0.36

Source: U.S. Centers for Disease Control and Prevention. (2025). NCHHSTP AtlasPlus [Interactive data tool]. National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention.

Classifications of persons with Stage 3 AIDS, by number of cases and percentage, 2023
	AI/AN	Total Population
Cumulative Cases^	3,691	1,366,381
Percent of Total Cases	0.3	100.00
^Cumulative data are from the beginning of the epidemic (1981) through 2023.

Source: U.S. Centers for Disease Control and Prevention. (2025). HIV surveillance report: Diagnoses, deaths, and prevalence of HIV in the United States and 6 territories and freely associated states, 2023: Slide set: HIV infection, Stage 3 (AIDS) 2022 (Slide 6) [PowerPoint presentation]. U.S. Department of Health and Human Services.

Mortality

Human Immunodeficiency Virus (HIV)

Deaths of persons with diagnosed HIV infection, rate per 100,000 population, 2023
	AI/AN	Total Population	Ratio (AI/AN / Total)
Male	4.1	8.7	0.47
Female	1.9	2.5	0.76
Total Population	3.0	5.6	0.54

Source: U.S. Centers for Disease Control and Prevention. (2024). HIV surveillance report: Diagnoses, deaths, and prevalence of HIV in the United States and 6 territories and freely associated states, 2023 (Vol. 35, Tables 12a and 11a). U.S. Department of Health and Human Services.

Acquired Immune Deficiency Syndrome (AIDS)

Deaths of persons ages 13 and older with AIDS, rate per 100,000 population, 2023
	AI/AN	Total Population	Ratio (AI/AN / Total)
Male	3.2	7.7	0.42
Female	1.8	2.2	0.82
Both Sexes	2.5	4.9	0.51

Source: U.S. Centers for Disease Control and Prevention. (2025). NCHHSTP AtlasPlus [Interactive data tool]. National Center for HIV, Viral Hepatitis, STD, and Tuberculosis Prevention.

Health Care Use

HIV testing status among persons ages 18 and over, age-adjusted percentage, 2018
	AI/AN	Total Population	Ratio (AI/AN / Total)
Ever tested	46.6	43.7	1.07
Never tested	53.4	56.3	0.95

Source: U.S. Centers for Disease Control and Prevention. (2021). Summary health statistics for U.S. adults: 2018 (Table A-20a). U.S. Department of Health and Human Services.

*Population is non-Hispanic in the data source.

1 Centers for Disease Control and Prevention (CDC), 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 3a and 1a. (Back to top)

2 CDC, 2024. HIV Surveillance Report: Diagnoses, Deaths, and Prevalence of HIV in the United States and 6 Territories and Freely Associated States, 2023, v.35. Tables 12a and 11a. (Back to top)

3 CDC. NCHHSTP Atlas Plus. https://gis.cdc.gov/grasp/nchhstpatlas/tables.html (Back to top)

Date Last Reviewed: January 2026