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Chronic Liver Disease and American Indians/Alaska Natives

Among American Indians and Alaska Natives, chronic liver disease is a leading cause of death. While the cause is not always known, some cases can be initiated by conditions such as chronic alcoholism, obesity, and exposure to hepatitis B and C viruses.

  • In 2018, chronic liver disease was the fourth leading cause of death for all American Indians/Alaska Natives, and the third leading cause of death for American Indian/Alaska Native men, ages 35-44. 1
  • American Indians/Alaska Natives are 1.6 times more likely to be diagnosed with chronic liver disease as compared to non-Hispanic whites.
  • The overall death rate for American Indians/Alaska Natives is three times higher than the non-Hispanic white population.
  • American Indian/Alaska Native women are 2.3 times as likely to be diagnosed with chronic liver disease and 4.4 times more likely to die from chronic liver disease as compared to non-Hispanic white women.

Cancer Rates for American Indian/Alaska Natives (2012-2016)

Cancer Incidence Rates per 100,000 – Men
Cancer American Indian/Alaska Native Men Non-Hispanic White Men American Indian/Alaska Native / Non-Hispanic White Ratio
All Sites 315.3 505.5 0.5
Liver & IBD* 19.3 10.8 1.8

Source: NCI 2020. Seer Cancer Statistics Review, 1975-2016. Tables 2.15 through 24.15
https://seer.cancer.gov/csr/1975_2016/sections.html

 

Cancer Incidence Rates per 100,000 – Women

Cancer American Indian/Alaska Native Women Non-Hispanic White Women American Indian/Alaska Native / Non-Hispanic White Ratio
All Sites 306.0 448.0 0.7
Liver & IBD* 8.5 3.7 2.3

Source: NCI 2020. Seer Cancer Statistics Review, 1975-2016. Tables 2.15 through 24.15
https://seer.cancer.gov/csr/1975_2016/sections.html  

 

Diagnosed

Age-adjusted percentage of persons 18 years of age and over who have been told by a doctor that they have chronic liver disease, 2018
American Indian/Alaska Native Non-Hispanic White American Indian/Alaska Native / Non-Hispanic White Ratio
2.5 1.6 1.6

Source: CDC 2020. Summary Health Statistics: National Health Interview Survey: 2018. Table A-4a. http://www.cdc.gov/nchs/nhis/shs/tables.htm

 

Death Rates (2012-2016)

Cancer Death Rates per 100,000 – Men
Cancer: Liver & IBD*
Region American Indian/Alaska Native Men Non-Hispanic White Men American Indian/Alaska Native / Non-Hispanic White Ratio
Total U.S. 9.9 8.3 1.2
PRCDA Counties** 14.4 8.3 1.7
Non-PRCDA Counties 5.1 8.3 0.6

 Source: NCI 2020. Seer Cancer Statistics Review, 1975-2016. Table 14.15
https://seer.cancer.gov/csr/1975_2016/results_single/sect_14_table.15.pdf  [PDF | 11.16KB]

 

Cancer Death Rates per 100,000 – Women
Cancer: Liver & IBD*

Region American Indian/Alaska Native Women Non-Hispanic White Women American Indian/Alaska Native / Non-Hispanic White Ratio
Total U.S. 5.1 3.4 1.5
PRCDA Counties** 7.4 3.4 2.2
Non-PRCDA Counties 2.4 3.4 0.7

Source: NCI 2020. Seer Cancer Statistics Review, 1975-2016. Table 14.15
https://seer.cancer.gov/csr/1975_2016/results_single/sect_14_table.15.pdf  [PDF | 11.16KB]


*IBD = Intrahepatic Bile Duct
**IHS purchased/referred care delivery area (PRCDA)

 

Age-adjusted Chronic Liver Disease and Cirrhosis Death Rates per –100,000 (2017)
  Non-Hispanic American Indian/Alaska Native Non-Hispanic White Non-Hispanic American Indian/Alaska Native / Non-Hispanic White Ratio
Men 43.3 14.6 3.0
Women 35.4 8.2 4.4
Total 39.5 11.3 3.5

Source: CDC 2019. National Vital Statistics Report, Vol. 68, No. 9. Table 10.
https://www.cdc.gov/nchs/data/nvsr/nvsr68/nvsr68_09-508.pdf [PDF | 1.76MB]

 

1 CDC, National Center for Injury Prevention and Control. Web-based Injury Statistics Query and Reporting System (WISQARS)
http://www.cdc.gov/injury/wisqars/fatal.html

Last Modified: 3/13/2020 11:42:00 AM